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Diagnosis of West Nile virus infection is through detection of?

1) viral growth in cell cultures
2) a rise in neutralizing antibody in a patient's serum
3) PCR analysis from saliva samples
4) culture on artificial media

1 Answer

1 vote

Final answer:

The diagnosis of West Nile virus infection is typically done through serologic tests to detect a rise in neutralizing antibodies and PCR to detect viral genetic material in patient samples.

Step-by-step explanation:

Diagnosis of West Nile virus infection is primarily through the detection of a rise in neutralizing antibody in a patient's serum, particularly with the help of serologic tests. Additionally, Polymerase Chain Reaction (PCR) can be used to detect the viral genetic material in a sample, which may include blood, cerebrospinal fluid, or tissue samples. Cultivation of the virus from samples such as saliva is less common, especially in early diagnosis. Methods like virus isolation in cell cultures can be used for research purposes but are not typically the first choice in clinical settings due to their complexity and time requirements.

The diagnosis of West Nile virus infection is typically done through detection of viral growth in cell cultures, a rise in neutralizing antibody in a patient's serum, and PCR analysis from saliva samples. Culture on artificial media is not commonly used for diagnosis of West Nile virus infection.

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