Final answer:
IgG1 and IgG3 are the antibodies involved in opsonization, a process that marks pathogens for destruction by phagocytes.
Step-by-step explanation:
The question at hand is asking about which antibodies are involved in opsonization, which is a process where antibodies coat a pathogen to flag it for destruction by phagocytic cells like macrophages. Among the antibodies listed, both IgG1 and IgG3 are known to be involved in opsonization. IgD is not typically associated with this process. Therefore, the correct answer to the question would be option 4: Only IgG1 and IgG3. IgG antibodies play a significant role in the immune response, with the IgG class being able to cross the placenta and activating complement proteins which aid in opsonization and pathogen clearance from the blood.