Final answer:
HIV-2 differs from HIV-1 in terms of geographic distribution and genetic mutations. The CCR5-delta 32 mutation provides some protection from HIV infection. HIV's ability to mutate quickly within the body leads to individual drug resistance.
Step-by-step explanation:
HIV-2 differs from HIV-1 in a number of properties. One of these differences is that HIV-2 is concentrated in West Africa, whereas HIV-1 occurs in human populations worldwide. Another difference is that individuals of Eurasian descent may have a deletion mutation, called CCR5-delta 32, that provides some protection from HIV infection. This mutation prevents HIV from effectively binding to a coreceptor on T cells, blocking viral entry. Lastly, HIV has a tendency to mutate quickly within the body, leading to individual drug resistance and requiring a different treatment strategy.