Final answer:
Infants who had a congenital infection with Treponema pallidum may exhibit wide spacing and central notching of teeth, characteristic of congenital syphilis.
Step-by-step explanation:
Wide spacing and central notching of teeth in infants may be observed in cases where there has been a congenital infection with Treponema pallidum, the bacterium responsible for syphilis. Children born with congenital syphilis can show symptoms that mimic those of secondary syphilis, such as mucus patches that may deform the nose, and gummas which can cause significant tissue damage to organs and teeth. As a preventative measure, expectant mothers are often screened for syphilis during the first trimester of pregnancy using the TORCH panel of prenatal tests to mitigate the risks associated with congenital syphilis.