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---------------: Formed by blood flowing in opposite directions in adjacent parallel capillaries of the vasa recta.

1. vasa recta
2. impermeable
3. kidneys
4. Ureter

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Final answer:

The vasa recta, alongside the loops of Henle, form a portal system in the kidneys that enables the countercurrent multiplier system, crucial for the reabsorption of solutes and water and the concentration of urine. Slow blood flow is necessary for this system to allow the exchange of nutrients, wastes, and the preservation of osmolar gradients.

Step-by-step explanation:

Formed by blood flowing in opposite directions in adjacent parallel capillaries of the vasa recta, this system plays a critical role in the kidneys' ability to concentrate urine and conserve water. The vasa recta are branches of the efferent arterioles that run alongside the loops of Henle. These capillaries form part of a unique portal system along with the glomerulus and are continuous with the peritubular capillaries. They participate in the countercurrent multiplier system, which allows for efficient reabsorption of solutes and water. This process is vital to prevent the excessive loss of water from the body, which would otherwise lead to the production of a large volume of urine (20-25 liters). Instead, by reabsorbing water and solutes such as Na+ and urea at a rate that maintains the osmolar gradient essential for this recovery, the kidneys produce a much smaller volume of concentrated urine.

The rate of blood flow in the vasa recta must be slow to allow sufficient time for exchange between blood and the surrounding medullary tissue, without causing damage to blood cells or disrupting the osmotic gradient necessary for water reabsorption. As the vasa recta capillaries descend into the medulla, they freely allow Na+ and urea to enter while water exits. As they ascend, Na+ and urea are secreted back into the medulla, and water is reabsorbed. This mechanism is critical to the kidneys' ability to concentrate urine and maintain proper fluid balance.

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