Question

Which of the following reactions gives rise to NADH molecule?

a. Glucose --> Glucose 6-phosphate
b. alpha ketoglutarte --> succinyl CoA
c. Citrate --> cis-aconitate
d. Succinate --> Fumarate
e. Fumarate --> malate

Answer 1

The production of NADH occurs during the oxidative decarboxylation of isocitrate to α-ketoglutarate in the Citric Acid Cycle.

Step-by-step explanation:

The reaction that gives rise to an NADH molecule among the options provided is a. isocitrate into α-ketoglutarate. This step occurs in the Citric Acid Cycle and involves the oxidative decarboxylation of isocitrate. The enzyme isocitrate dehydrogenase facilitates this reaction, which results in the conversion of isocitrate to α-ketoglutarate, along with the reduction of NAD+ to NADH. Additionally, three NADH molecules are produced on each turn of the Citric Acid Cycle, which includes the steps mentioned above, succinyl CoA into succinate, and malate into oxaloacetate.