Final answer:
The enzyme responsible for splitting a six-carbon molecule into two three-carbon molecules in glycolysis is fructose bisphosphate aldolase.
Step-by-step explanation:
The enzyme which splits a six-carbon molecule into two three-carbon molecules in glycolysis is called fructose bisphosphate aldolase. During glycolysis, fructose 1,6-bisphosphate, a six-carbon sugar, is split into two three-carbon molecules: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. The enzyme aldolase catalyzes this important reaction facilitating the cleavage of the six-carbon sugar into these two three-carbon isomers.
Therefore, the correct answer to the question is e. Fructose bisphosphate aldolase. This reaction is crucial for the continuation of glycolysis, allowing the two three-carbon molecules to be further processed down the glycolytic pathway, eventually leading to the production of ATP and pyruvate.