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What component of the proximal tubule, if not functional, would have the most severe effect on kidney function?

User DiegoRBaquero
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Answer: The Na+/K+ ATPase

Explanation: Located on the basolateral aspect of tubule cells, renal Na-K-ATPase plays a key role in the active translocation of Na and K across this membrane as well as in the "secondary active" transport of a number of other solutes.

User Stephen Sprinkle
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