Final answer:
Hemoglobin C disease is an autosomal recessive genetic disorder affecting hemoglobin and is a common adaptation in regions with a high incidence of malaria.
Step-by-step explanation:
The mode of inheritance of Hemoglobin C disease is typically autosomal recessive. This means that both parents must carry one copy of the mutated gene to pass the disease to an offspring. If both parents carry the trait, there is a 25% chance their child will be affected, a 50% chance the child will be a carrier, and a 25% chance the child will neither carry nor be affected by the trait. Hemoglobin C disease involves an abnormal hemoglobin variant and is a genetic adaptation to malaria, commonly found in West and North Africa.