Question

What is the most common enzymatic disorder of RBCs?
1) G6PD deficiency
2) Other

Answer 1

1) G6PD deficiency. The most common enzymatic disorder of RBCs is G6PD deficiency, which occurs most frequently in African-American males. Female carriers may also be affected due to random X-chromosome inactivation.

Step-by-step explanation:

The most common enzymatic disorder of red blood cells (RBCs) is G6PD deficiency. G6PD deficiency is a genetic condition that results in a shortage of the enzyme glucose-6-phosphate dehydrogenase, which is necessary to prevent the abnormal breakdown of red blood cells. Without this enzyme, red blood cells break down prematurely, leading to anemia. G6PD deficiency occurs most frequently in African-American males. Female carriers may also be affected to varying degrees due to random inactivation of one X-chromosome.