Question

Certain drugs (e.g. penicillin) bind to RBC membranes, leading to the formation of antibodies against the drug-RBC complex. This condition is known as:

1) IgG-mediated hemolytic anemia
2) IgM-mediated hemolytic anemia
3) IgA-mediated hemolytic anemia
4) IgE-mediated hemolytic anemia

Answer 1

Certain drugs binding to RBC membranes and leading to antibodies against the drug-RBC complex is known as IgG-mediated hemolytic anemia.

Step-by-step explanation:

The condition described in the question, where certain drugs bind to red blood cell (RBC) membranes and lead to the formation of antibodies against the drug-RBC complex, is known as IgG-mediated hemolytic anemia. In this type II hypersensitivity reaction, the antibodies involved are primarily IgG, rather than IgM, IgA, or IgE. This reaction can occur in conditions such as hemolytic transfusion reaction (HTR) and hemolytic disease of the newborn (HDN).