Final answer:
Drug-induced immune hemolytic anemia is typically mediated by IgG due to Type II (Cytotoxic) Hypersensitivities, where IgG and IgM target drug-altered red blood cells, causing destructive immune responses as part of iatrogenic disease.
Step-by-step explanation:
Drugs can cause a form of immune hemolytic anemia that is mediated by IgG. This type of hemolytic anemia is a result of Type II (Cytotoxic) Hypersensitivities, where IgG and IgM antibodies can bind to cell-surface antigens. The involvement of these antibodies can activate complement, leading to an inflammatory response and the lysis or destruction of the targeted cells such as red blood cells. Specifically in drug-induced cases, these reactions are often associated with certain medications that can bind to red blood cell surfaces, altering their structure and making them targets for immune response. These drug-induced immune reactions can sometimes cause the body to mistakenly recognize its own red blood cells as foreign due to the presence of the drug, leading to a cytotoxic reaction where IgG antibodies attack the red blood cells, resulting in hemolytic anemia. This can be exemplified by drug-induced hemolytic anemia, where drugs such as certain antibiotics or antiepileptics can lead to the production of these antibodies. The concept of iatrogenic disease includes conditions such as drug-induced hemolytic anemia that are acquired during medical treatment with drugs.