Final answer:
The acronym CHOP stands for a chemotherapy regimen including Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone, and is used in treating non-Hodgkin's lymphoma.
Step-by-step explanation:
The acronym CHOP stands for a chemotherapy regimen used in the treatment of non-Hodgkin's lymphoma. The letters in CHOP represent the following chemotherapeutic agents: Cyclophosphamide, Doxorubicin (whose old trade name was Hydroxydaunorubicin), Vincristine (whose old trade name was Oncovin), and Prednisone. Thus, the correct option for the CHOP chemotherapy cocktail is:
Cyclophosphamide, Doxorubicin, Vincristine, Prednisone
This combination chemotherapy is part of a strategy to use multiple drugs with different mechanisms of action to prevent cancer cells from developing resistance. It has its origins in the foundational work by Holland, Freireich, and Frei with the POMP regimen, a concept that has been refined and extended in later years to treat various types of cancer effectively, including lymphomas.