Final answer:
Before IV administration of amphotericin B, premedications like antihistamines, steroids, and antiemetics are recommended to reduce potential side effects such as allergic reactions and nausea.
Step-by-step explanation:
Prior to administering amphotericin B via IV, it is recommended to give medications to help mitigate some of its potential side effects such as infusion-related reactions. These premedications often include antihistamines, steroids, and antiemetics. Antihistamines and steroids are particularly useful for preventing allergic reactions and reducing inflammation, which can be aligned with type III hypersensitivity reactions treatment such as anti-inflammatory steroid treatments. Antiemetics help manage nausea that can be induced by amphotericin B. In stark contrast, anti-anxiety medications do not serve as routine premedication for amphotericin B, as they do not address the direct physiological effects of the drug.