Final answer:
True, the acquisition of land was the most important motivating factor in the formulation of early U.S. Indian policy, aligning with expansionist desires and Manifest Destiny.
Step-by-step explanation:
The acquisition of land was indeed a primary motivating factor in the formulation of early U.S. Indian policy. This objective was in line with the country's expansionist desires and the ideology of Manifest Destiny, which held that the United States was destined to expand across the North American continent. The desire for land drove many treaties and resulted in the relocation and disenfranchisement of Native American tribes.