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What happens during acute catabolic phase of an injury, infection, or surgery? What decreases as a result?

User Riffraff
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Final answer:

During the acute catabolic phase of an injury, infection, or surgery, the body ramps up the breakdown of molecules for energy resulting in increased energy expenditure and a decrease in protein stores and muscle mass.

Step-by-step explanation:

Acute Catabolic Phase in Response to Injury, Infection, or Surgery

During the acute catabolic phase of an injury, infection, or surgery, the body undergoes significant metabolic changes. These changes include increased catabolic reactions where large molecules such as proteins, lipids, and carbohydrates are broken down into their constituent smaller parts like amino acids, fatty acids, and monosaccharides. This process is crucial for prompt energy provision necessary to respond to the stress of injury, facilitate repair, and combat infection. Consequently, there is an increase in energy expenditure and a decrease in overall protein stores due to the breakdown of muscle protein to supply amino acids for energy and repair purposes.

As energy needs go up, the body utilizes its reserve of nutrients to fuel the repair process. The result of these heightened catabolic activities includes a decrease in muscle mass, because proteins are diverted away from the anabolic processes, which are responsible for muscle synthesis and growth, to support the immediate needs of healing and immune function.

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