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What is the protein electrophoresis pattern typically seen in Multiple Myeloma?

a) Decreased gamma globulins
b) Increased gamma globulins
c) Decreased alpha globulins
d) Increased beta globulins

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Final answer:

In Multiple Myeloma, protein electrophoresis typically reveals an increase in gamma globulins, characterized by a sharp spike on the densitometer scan in the gamma region, indicating the presence of monoclonal proteins.

Step-by-step explanation:

The protein electrophoresis pattern typically seen in Multiple Myeloma is increased gamma globulins. In patients with Multiple Myeloma, the electrophoresis gel will display a distinct band in the gamma globulin region. This is due to the production of abnormal antibodies, which are monoclonal proteins (M proteins), leading to a sharp spike on the densitometer scan of the protein electrophoresis. This sharp spike is in contrast to the normal broad smear seen in the gamma globulin region of individuals without Multiple Myeloma. Elevated serum protein levels and the presence of Bence Jones proteins in the urine can also aid in the diagnosis of this condition.

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