Question

What are the six factors that determine serum albumin?

Answer 1

The six factors that determine serum albumin are concentration, synthesis, pH, migration, protein structure, and coagulation.

Step-by-step explanation:

The six factors that determine serum albumin include:

1. Concentration: Serum albumin is present in the blood at a concentration of 3.5-5.5 gms/100 ml.
2. Synthesis: It is synthesized in the liver.
3. pH: Albumin has a low isoelectric pH of 4.7.
4. Migration: It migrates fastest in electrophoresis and precipitates last in salting out or alcohol precipitation methods.
5. Protein structure: It is a simple protein containing large amounts of essential amino acids.
6. Coagulation: Albumin coagulates on heating and precipitates on full saturation with ammonium sulphate.