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Factor XII deficiency causes?

a) Hemophilia A
b) Hemophilia B
c) Hereditary angioedema
d) Factor V Leiden mutation

1 Answer

3 votes

Final answer:

Factor XII deficiency is not associated with Hemophilia A, Hemophilia B, hereditary angioedema, or Factor V Leiden mutation; thus, none of the options (a through d) correctly identify the consequence of a deficiency in factor XII.

Step-by-step explanation:

Factor XII deficiency does not cause hemophilia A or B, as these disorders are related to deficiencies of factor VIII and factor IX, respectively. Hemophilia A is characterized by a deficiency of factor VIII, while hemophilia B is a result of insufficient factor IX. Neither condition is caused by an issue with factor XII. The mention of factor V Leiden mutation is also unrelated to factor XII; instead, it is a genetic mutation that increases the risk of blood clots. Factor XII deficiency is most closely associated with a rare autosomal disorder that affects the intrinsic clotting pathway but is not typically related to any of the causes mentioned in the options (a through d).

The correct association for factor XII deficiency is not provided among the given choices. Therefore, a conclusion that factor XII deficiency causes any of the conditions listed (a) Hemophilia A, (b) Hemophilia B, (c) Hereditary angioedema, or (d) Factor V Leiden mutation would be incorrect. In reality, factor XII deficiency can lead to an increased risk of clotting due to its role in the intrinsic pathway of the clotting mechanism, but it does not fit the profiles of the conditions listed in the question.

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