Final answer:
It takes three nucleotides, known as a codon, of an RNA molecule to code for a single amino acid.
Step-by-step explanation:
The question asks how many 'letters' of an RNA molecule are needed to code for a single amino acid. In the context of molecular biology, the 'letters' refer to nucleotides, which are the basic building blocks of RNA. Three consecutive nucleotides, known as a codon, are required to specify an amino acid in the synthesis of proteins. Therefore, the answer to the question is c) 3.