Question

Where might you see abnormal cells on a VCS (Variable Cell Sizing) scatterplot?

A) Abnormal cells would appear within the normal cell population on the scatterplot.

B) Abnormal cells would be outside the normal cell population, showing distinct clusters.

C) Abnormal cells would not be visible on the scatterplot.

D) Abnormal cells would be indicated by a different color, not their position on the scatterplot.

Answer 1

Abnormal cells would appear outside the normal cell population on a VCS scatterplot, forming distinct clusters separate from the typical pattern of normal cells. This is crucial for the early detection and diagnosis of diseases.

Step-by-step explanation:

On a VCS (Variable Cell Sizing) scatterplot, abnormal cells would be depicted outside the normal cell population, showing distinct clusters. This means that the correct answer is B) Abnormal cells would be outside the normal cell population, showing distinct clusters. In flow cytometry and similar analyses, the data from forward- and side-scatter detectors can discern the physical and chemical characteristics of cells. Normal cells are expected to form a predictable pattern, while abnormal cells, such as those observed in some diseases or disorders, may present with a different size or granularity, leading to their representation in distinct clusters away from the typical cell population.

This principle is essential in the diagnostic process. It allows cytotechnologists and pathologists to determine which cellular changes are within normal limits and which are abnormal. Identifying abnormal cells early can allow for a more timely diagnosis and treatment, increasing the chances of a successful outcome.