Final answer:
Anemia of chronic disease is characterized by decreased serum iron, decreased total iron-binding capacity, decreased transferrin saturation, and normal or increased ferritin levels.
Step-by-step explanation:
Anemia of chronic disease is characterized by decreased serum iron, along with decreased total iron-binding capacity and decreased transferrin saturation. However, the ferritin levels in anemia of chronic disease are usually normal or increased. So, the correct answer is option 4) All of the above.