Final answer:
True. Intra-vascular hemolysis involves the destruction of red blood cells within vessels, which can occur during hemolytic disease of the newborn or when there is a mismatched blood transfusion.
Step-by-step explanation:
True. Intra-vascular hemolysis is the destruction of red blood cells (RBCs) within blood vessels. This can occur in situations such as mismatched blood transfusions or during hemolytic disease of the newborn. When RBCs are destroyed within vessels, it can lead to the release of hemoglobin and other cell contents into the bloodstream, causing various symptoms and complications.