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One normal type of hemoglobin is HbF which is composed of two α and two γ chains, i.e. α2γ2?

1) True
2) False

1 Answer

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Final answer:

The statement is true; HbF or fetal hemoglobin is comprised of two alpha and two gamma chains (α2γ2) and facilitates oxygen transfer from the mother to the fetus.

Step-by-step explanation:

The statement that one normal type of hemoglobin is HbF, which is composed of two α and two γ chains, i.e., α2γ2, is True.

Hemoglobin is an essential protein in red blood cells responsible for transporting oxygen throughout the body. It's composed of four globin chains. In adults, the most common form of hemoglobin is HbA, which consists of two alpha (α) and two beta (β) chains. Another variant, HbA2, also occurs in some individuals and includes two alpha and two delta (δ) chains.

HbF, also known as fetal hemoglobin, predominates in the growing fetus and is made up of two alpha (α) and two gamma (γ) chains. This composition facilitates the efficient transfer of oxygen from mother to fetus. After birth, HbF gradually gets replaced by adult forms of hemoglobin. Disorders of hemoglobin, like thalassemias, result from imbalances in the synthesis of alpha or beta chains and can lead to serious health difficulties due to impaired oxygen transport.

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