Final answer:
Capsaicin, the compound found in peppers, creates a burning sensation when it interacts with receptors in our body that are responsible for sensing heat. Handling capsaicin with bandages can lead to serious burning and skin irritation.
Step-by-step explanation:
Capsaicin, the compound found in peppers, creates the sensation of spiciness or heat due to its interaction with certain receptors in our body. When capsaicin comes into contact with the tongue or skin, it binds to receptors called VR1 receptors, which are primarily responsible for sensing heat. This binding triggers a series of events that lead to the perception of a burning sensation.
The reason capsaicin feels hot is because it activates the same receptors that respond to actual heat. This results in the release of neurotransmitters that signal the brain, causing it to interpret the stimulation as heat or pain. The more capsaicin present, the stronger the burning sensation.
When handling capsaicin or products containing it, it is advised not to cover it with bandages. This is because the capsaicin can penetrate through the bandage and continue to stimulate the VR1 receptors, causing a potentially serious burning sensation and skin irritation.