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A patient with end stage liver disease with refractory ascites awaiting liver transplantation is on PN due to intolerance to tube feeding. His sodium is 124 mEq/L. Which of the following changes to his PN prescription is most appropriate to recommend?

1: Restrict fluid, supplement sodium, provide 2.5g protein/kg per day
2: Restrict fluid, restrict sodium , provide 0.5 g protein/kg per day
3: Restrict fluid, restrict sodium, provide 1.5 g protein/kg per day
4: Restrict fluid, supplement sodium, provide 1.0 g protein/kg per day

User Rystraum
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1 Answer

4 votes

Final answer:

For a patient with end stage liver disease and refractory ascites awaiting transplantation, it is recommended to restrict fluid, supplement sodium due to the low serum sodium, and provide a moderate protein provision of 1.0 g protein/kg per day, as indicated in option 4.

Step-by-step explanation:

The most appropriate recommendation for a patient with end stage liver disease and refractory ascites who is awaiting transplantation and has a sodium level of 124 mEq/L would be to make specific adjustments to the parenteral nutrition (PN) prescription. Given the low sodium, it would be usual to supplement sodium. However, in patients with end-stage liver disease, especially with conditions such as ascites, managing sodium and fluid balance is crucial. The patient's low serum sodium does not necessarily indicate a total body sodium deficit; in fact, the ascites suggest fluid overload, which likely represents dilutional hyponatremia. Therefore, fluid restriction is appropriate.

In terms of protein provision, while adequate protein intake is necessary to support the patient's nutritional needs and liver function, careful attention must be paid to avoid excess protein which could potentially contribute to hepatic encephalopathy. A moderate protein intake of around 1.0 to 1.5 g protein/kg per day is often used in clinical practice for this patient group based on their individualized needs.

Therefore, option 4: Restrict fluid, supplement sodium, provide 1.0 g protein/kg per day would likely be the best choice among the options provided. It is important that these recommendations be tailored to the specific needs of the patient and monitored closely given that intravenous sodium and fluid management can be complex in end-stage liver disease.

User Nenick
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