Final answer:
The correct answer is B) Kidney, diabetes, third, as NSAIDs should be avoided with kidney failure, uncontrolled diabetes, and during the third trimester of pregnancy due to the risk of complications like kidney damage and harmful effects on the fetus.
Step-by-step explanation:
NSAIDs should be avoided in patients with kidney failure, uncontrolled diabetes, and during the third trimester of pregnancy. Therefore, the correct answer is B) Kidney, diabetes, third. NSAIDs can cause kidney damage, especially in people who are over the age of 60, are taking diuretics, have high blood pressure, heart disease, or pre-existing kidney disease. Acetaminophen is an alternative to NSAIDs but in acute overdose can cause severe liver damage. ACE inhibitors, not NSAIDs, are known to cause fetal renal failure and complications during pregnancy. It is essential to avoid NSAIDs during the third trimester as they can cause issues like pulmonary hypoplasia and limb contracture in the fetus due to compromised renal function.