Question

Death of patients with I-cell disease usually occurs by age:

a) 8-10 years
b) 20-30 years
c) 40-50 years
d) 60-70 years

Answer 1

Patients with I-cell disease typically do not survive past childhood due to the severe complications. The correct answer to the expected lifespan is 8-10 years.

Step-by-step explanation:

I-cell disease, also known as mucolipidosis II, is a rare and progressive metabolic disorder that affects many parts of the body. Generally, infants with I-cell disease develop multiple organ problems and cognitive impairment. One of the distinct characteristics of the disease is that affected individuals have coarse facial features and skeletal abnormalities. Unfortunately, I-cell disease is typically severe and leads to an early childhood death.

Based on medical knowledge about I-cell disease, patients with this condition usually do not survive past childhood. The correct answer to the question is a) 8-10 years. Beyond that age range, complications from the disease, such as restrictive lung disease and heart problems, among other complications, make survival unlikely.