Final answer:
The major portal of entry for Aspergillus is the respiratory tract. Mucosal surfaces, including the respiratory tract, gastrointestinal tract, and genitourinary tract, are important portals of entry for microbes.
Step-by-step explanation:
The major portal of entry for Aspergillus is the respiratory tract. Aspergillosis is a fungal disease caused by molds of the genus Aspergillus. In secondary cutaneous aspergillosis, the fungus enters via the respiratory system and disseminates systemically. Mucosal surfaces, including the respiratory tract, gastrointestinal tract, and genitourinary tract, are important portals of entry for microbes.