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X inactivation is controlled by the _____ gene.

a)SRY
b)androgen insensitivity
c)female-determining
d)XIST
e)None of the above answers is correct.

1 Answer

1 vote

Final answer:

Option (d), The gene responsible for X inactivation in female mammals is the XIST gene, which leads to the condensation of one of the X chromosomes into a Barr body.

Step-by-step explanation:

X inactivation is controlled by the XIST gene. This process occurs early in development when female mammalian embryos consist of just a few thousand cells. One X chromosome in each cell inactivates by condensing into a structure called a Barr body, which is visible in the nucleus.

The particular X chromosome that is inactivated is random, but once inactivation occurs, all cells descended from that cell will have the same inactive X chromosome. In human females and certain other mammals like the female fruit flies, this compensates for their double genetic dose of X chromosome genes.

Therefore, the correct answer to the student's question is: X inactivation is controlled by the XIST gene.

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