Final answer:
The circumstances considered adulteration under the FDCA include preparing and packaging drugs under unsanitary conditions, non-conformance of manufacturing procedures to GMP standards, and non-compliance with the Poison Prevention Packaging Act.
Step-by-step explanation:
Under the FDCA (Food, Drug, and Cosmetic Act), circumstances that would be considered adulteration include:
- A drug being prepared and packaged under unsanitary conditions.
- The drug's manufacturing procedures not conforming to GMP (Good Manufacturing Practice) standards.
- The drug being subject to the Poison Prevention Packaging Act and not being packaged accordingly.
Therefore, the correct answer is e. a, b, and c.