Final answer:
Giovanni da Verrazzano was the Italian explorer who reached the Cape Fear River mouth in 1524.
Step-by-step explanation:
The Italian explorer who made it to the Cape Fear River mouth in 1524 was Giovanni da Verrazzano. Unlike Christopher Columbus, Verrazzano understood that the Americas were not part of Asia but previously unknown lands to Europeans. His voyages and accounts sparked interest in the New World among Europeans.