Question

Certain drugs (e.g. penicillin) bind to RBC membranes, leading to the formation of antibodies against the drug-RBC complex. This condition is known as:

1) IgG-mediated hemolytic anemia
2) IgM-mediated hemolytic anemia
3) IgA-mediated hemolytic anemia
4) IgE-mediated hemolytic anemia

Answer 1

Certain drugs (e.g., penicillin) binding to RBC membranes, leading to the formation of antibodies against the drug-RBC complex, result in IgG-mediated hemolytic anemia. Option 1 is the answer.

Step-by-step explanation:

In drug-induced hemolytic anemia, the immune system can recognize drug molecules bound to red blood cell (RBC) membranes as foreign. This recognition triggers the production of antibodies against the drug-RBC complex. In this scenario, the type of immunoglobulin involved is primarily IgG.

Therefore, the correct answer is option 1) IgG-mediated hemolytic anemia. IgG antibodies can lead to the destruction of RBCs, causing anemia. It's essential to identify the specific antibody involved in drug-induced hemolytic anemia, as it influences the clinical manifestations and management of the condition.

Option 1 is the answer.