Question

RBCs are normally exposed to oxidative stress, especially by H₂O₂ chemical. What is the effect of oxidative stress on RBCs?

1) Decreased lifespan of RBCs
2) Increased lifespan of RBCs
3) No effect on lifespan of RBCs
4) Cannot be determined

Answer 1

Oxidative stress caused by reactive oxygen species (ROS) can lead to damage to the cellular components of red blood cells (RBCs), resulting in decreased lifespan, increased hemolysis, and anemia. Additionally, oxidative stress is believed to be a major contributor to aging and the development of various age-related diseases.

Step-by-step explanation:

Oxidative stress caused by reactive oxygen species (ROS) can lead to damage to the cellular components of red blood cells (RBCs). This includes lipid peroxidation, protein oxidation, and DNA damage. The resulting effects of oxidative stress on RBCs include decreased lifespan, as well as increased hemolysis and anemia such as sickle cell anemia. Additionally, oxidative stress is believed to be a major contributor to aging and the development of various age-related diseases.