Final answer:
The neutrophil is the leukocyte most involved in an acute inflammatory response.
Step-by-step explanation:
The leukocyte that is most involved in an acute inflammatory response is the neutrophil. Neutrophils are a type of phagocytic leukocyte that engulf and digest pathogens. They are the most abundant leukocytes in the immune system and are attracted to the site of infection through chemical signals released during inflammation.