Question

Survivin is an apoptosis inhibitor in humans. If the survivin gene is mutated and a non-functional Survivin protein is made, which of the following would be the most likely effect on limb formation? A. mitosis of the limb bud cells would not occur

B. cells would not migrate to their correct position
C. cell determination would not occur
D. cell differentiation would not occur
E. webbing between digits would not be removed

Answer 1

If the survivin gene is mutated and a non-functional Survivin protein is made, the most likely effect on limb formation would be that webbing between digits would not be removed.

Step-by-step explanation:

If the survivin gene is mutated and a non-functional Survivin protein is made, the most likely effect on limb formation would be that webbing between digits would not be removed. Apoptosis, which is regulated by survivin, plays a crucial role in the elimination of unneeded cells during embryological development.

In vertebrates, web-like tissue between individual fingers and toes is formed in the early stages of development. Apoptosis is responsible for destroying these unneeded cells, resulting in the separation of fully formed digits If the survivin protein is non-functional due to a gene mutation, the cells between the developing digits would not be eliminated, and the webbing between digits would not be removed.