Final answer:
Nestorius was appointed to be Bishop in the year 453 AD.
Step-by-step explanation:
The correct answer is B) 453.
Nestorius was appointed to be Bishop in 453 AD.
Nestorius was a controversial figure in the early Christian Church, as he was accused of advocating a doctrine known as Nestorianism, which taught that Christ had two separate natures, human and divine. He was ultimately condemned as a heretic and deposed in the year 431 AD at the Council of Ephesus.