Final answer:
During the plague, people in medieval Europe employed various methods to try and save themselves, including fleeing from urban centers and implementing quarantine measures. Religious practices were also common as people sought divine intervention and protection. However, medical understanding of the plague was limited, and treatments were ineffective.
Step-by-step explanation:
During the plague, people in medieval Europe employed various methods to try and save themselves. Some individuals who could afford it fled from the crowded urban centers to the countryside. Italian cities imposed quarantine and travel restrictions, closed markets, and prohibited gatherings for funerals. Plague hospitals were established for the infected. Additionally, religious practices, such as prayers and penitential acts, were used as a means of seeking divine intervention and protection. However, lacking a scientific understanding of contagion, medical practitioners were unable to fully explain or treat the plague.