Question

Which action is associated with blocking the COX-2 pathway?

A. Enhancing COX-1 Activity.
B. Inhibiting COX-2 Enzyme.
C. Inducing COX-3 Production.
D. Stimulating COX-4 Pathway.

Answer 1

Blocking the COX-2 pathway is associated with inhibiting COX-2 enzyme. This action is performed by nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and naproxen. COX-2 selective inhibitors, such as celecoxib, specifically block the COX-2 enzyme more than the COX-1 enzyme.

Step-by-step explanation:

Blocking the COX-2 pathway is associated with inhibiting COX-2 enzyme. Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and naproxen inhibit the cyclooxygenase (COX) enzyme, which is involved in the synthesis of prostaglandins.

COX-2 selective inhibitors, such as celecoxib, specifically block the COX-2 enzyme more than the COX-1 enzyme. These drugs are believed to have a lower risk of causing stomach problems compared to older NSAIDs.

By blocking the COX-2 pathway and inhibiting prostaglandin synthesis, these drugs can relieve pain, reduce inflammation, and lower fever.