Final answer:
True, antigen-antibody binding can trigger the destruction of target cells by immune cells such as macrophages, eosinophils, and NK cells through a process known as ADCC.
Step-by-step explanation:
True, antigen-antibody binding with antibodies attached to the target cell can indeed lead to its destruction by various types of immune cells such as macrophages, eosinophils, and NK cells. This is part of a process known as antibody-dependent cell-mediated cytotoxicity (ADCC). In ADCC, the Fab region of an IgG antibody binds to an antigen on the pathogen.
Effector cells, which include NK cells, macrophages, and eosinophils, attach to the Fc region of the antibody. This close proximity allows the effector cell to secrete cytotoxins like perforin and granzymes, which can kill the pathogen. Furthermore, eosinophils can become activated when IgE labels a parasite and, similarly to the NK cells' mechanism, can lead to the destruction of the target.