Final answer:
The Arena Chapel, also known as the Scrovegni Chapel, in Padua, Italy, is famous for Giotto di Bondone's fresco cycle that marks a transition towards naturalism and dimensionality in art.
Step-by-step explanation:
The chapel that is renowned for its fresco cycle by Giotto di Bondone and symbolizes a shift towards a more naturalistic and three-dimensional approach is the Arena Chapel, also known as the Scrovegni Chapel. The fresco cycle within the chapel showcases stories from the lives of Mary and Christ along the long walls. At the altar, Giotto depicted the Annunciation, while the entrance wall features the dramatic Last Judgment.
The Chapel was commissioned by Enrico Scrovegni, possibly as an act of atonement for his and his father's sin of usury. Giotto's groundbreaking naturalistic style in the Arena Chapel marked a significant deviation from the medieval spiritual representation and heralded the onset of the Italian Renaissance.