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What type of hypersensitivity reaction is characterized by an immediate release of proinflammatory mediators such as histamine, leading to symptoms like bronchoconstriction, edema, and eosinophil recruitment?

A. Type II hypersensitivity
B. Type III hypersensitivity
C. Type I hypersensitivity
D. Type IV hypersensitivity
E. Type V hypersensitivity

1 Answer

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Final answer:

The hypersensitivity reaction with an immediate release of histamine and other mediators causing bronchoconstriction and edema is known as Type I hypersensitivity, which is IgE-mediated and involves mast cell degranulation.

Step-by-step explanation:

The type of hypersensitivity reaction characterized by an immediate release of proinflammatory mediators such as histamine, leading to symptoms like bronchoconstriction, edema, and eosinophil recruitment is Type I hypersensitivity. This reaction is triggered by allergens which cause the binding of allergen-specific IgE to mast cells. Upon subsequent exposure to the allergen, these IgE molecules trigger mast cell degranulation, leading to an immediate allergic reaction. Type I hypersensitivity is also responsible for other allergic reactions, such as hay fever, hives, and anaphylaxis.

User Fernando Barbeiro
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