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What type of fluorescence pattern on kidney biopsy is typically associated with Goodpasture syndrome?

A. Smooth and uniform
B. Lumpy bumpy
C. Linear
D. Negative fluorescence

User Tabassum
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1 Answer

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Final answer:

The typical fluorescence pattern on kidney biopsy for Goodpasture syndrome is linear, caused by the linear deposition of immunoglobulins along the basement membranes. The correct option is C.

Step-by-step explanation:

The type of fluorescence pattern on kidney biopsy that is typically associated with Goodpasture syndrome is C. Linear fluorescence.

Goodpasture syndrome, also known as anti-glomerular basement membrane disease, is characterized by the presence of circulating anti-GBM antibodies that attack the glomerular basement membrane in the kidneys and often the alveolar basement membrane in the lungs.

This autoimmune response leads to a linear deposition of immunoglobulins, particularly IgG, along the basement membranes, which can be detected using direct immunofluorescence microscopy on a kidney biopsy specimen.

User Trudy
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