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Which type of major histocompatibility complex (MHC) presents processed peptides to T cells and is commonly found on macrophages?

A. MHC-I
B. MHC-II
C. MHC-III
D. MHC-IV
E. MHC-V

1 Answer

4 votes

Final answer:

The MHC type that presents processed peptides to T cells and is found on macrophages is MHC-II, which is exclusively expressed on antigen-presenting cells including macrophages, dendritic cells, and B cells.

Step-by-step explanation:

The type of major histocompatibility complex (MHC) that presents processed peptides to T cells and is commonly found on macrophages is MHC-II. MHC-II molecules are expressed exclusively on the surface of antigen-presenting cells (APCs) such as macrophages, dendritic cells, and B cells. These cells present abnormal or nonself pathogen antigens for the initial activation of T cells, and the presentation with MHC-II is essential for the immune response. In contrast, MHC-I molecules are found on all nucleated cells and present antigens to effector T cells involved in cellular immunity, including normal self-antigens and those from abnormal or nonself pathogens.

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