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In a tuberculosis patient, which type of cells recruit and activate mononuclear cells from the blood following exposure to the purified protein derivative (PPD)?

A. B cells
B. Macrophages
C. T cells
D. Neutrophils

1 Answer

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Final answer:

Macrophages are the cells that recruit and activate mononuclear cells from the blood following exposure to PPD in tuberculosis patients. They stimulate naïve T cells to become TH1 cells, which help in fighting the infection.

Step-by-step explanation:

In a tuberculosis patient, the type of cells that recruit and activate mononuclear cells from the blood following exposure to the purified protein derivative (PPD) are macrophages. These cells play a crucial role in the immune system as part of the body's defense against pathogens. Upon exposure to an infectious agent like Mycobacterium tuberculosis, macrophages can stimulate naïve T cells to become TH1 cells, which in turn secrete cytokines that bolster the macrophages' capabilities to digest and destroy the pathogens. Moreover, macrophages, along with dendritic cells and B cells, serve as important antigen-presenting cells, enhancing the body's ability to fight off infections.

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