Question

What is the primary role of immature myeloid-derived dendritic cells positioned in tissues?

a) Continuous sampling of extracellular debris for pathogen-associated molecular patterns (PAMPs) and loading of intracellular MHC Class II
b) Direct destruction of invading pathogens in the extracellular space
c) Promotion of inflammation through the release of proinflammatory cytokines
d) Activation of complement cascades in response to infection
e) Surveillance for viral infections in the lymph nodes

Answer 1

The primary role of immature dendritic cells in tissues is continuous sampling of extracellular debris for pathogen-associated molecular patterns (PAMPs) and loading of intracellular MHC Class II.

Step-by-step explanation:

The primary role of immature myeloid-derived dendritic cells positioned in tissues is continuous sampling of extracellular debris for pathogen-associated molecular patterns (PAMPs) and loading of intracellular MHC Class II. Dendritic cells act as antigen-presenting cells (APCs) that detect, engulf, and process antigens. They then present these antigens to other immune cells, such as T cells, in order to activate an immune response.