Question

Where are γδ T cells typically found?

a) Mucosal barrier of the gut
b) Peripheral blood
c) Bone marrow
d) Lymph nodes
e) Spleen

Answer 1

γδ T cells are typically found in the mucosal barrier of the gut, specifically in Peyer's patches in the small intestine. These cells sample potential pathogens and mount immune responses in the regional lymph nodes.

Step-by-step explanation:

γδ T cells are typically found in the mucosal barrier of the gut, specifically in structures called Peyer's patches (lymphoid follicles) in the small intestine. These cells play a role in immune responses in mucosal tissues by sampling potential pathogens from the intestinal lumen and mounting an immune response in the regional lymph nodes. Dendritic cells transport antigens to the lymph nodes where T cell responses are mounted.