Question

What is the result of cross-linking of lgE bound to the surfaces of basophils and mast cells?

a) Activation of the classical pathway of complement.
b) Release of lgA.
c) Cellular degranulation and release of vasoactive amine responsible for inflammation.
d) Release of lgG.

Answer 1

Cross-linking of IgE bound to mast cells and basophils leads to cellular degranulation and the release of vasoactive amines, causing inflammation.

Step-by-step explanation:

When IgE antibodies bound to mast cells and basophils are cross-linked by an allergen, it leads to cellular degranulation and the release of vasoactive amines, such as histamine and serotonin. This degranulation process is responsible for inflammation in allergic reactions.