Question

Which of the following statements is true regarding pattern recognition receptors (PRRs)?

a) PRRs can recognize host-associated molecules such as MHC class I molecules.
b) PRRs are somatically generated by B and T cells.
c) PRRs are able to bind to molecules widely expressed by microbes and host cells.
d) PRRs vary greatly between individuals.

Answer 1

Pattern recognition receptors (PRRs) are membrane-bound receptors that recognize characteristic features of a pathogen and molecules released by stressed or damaged cells. They play a crucial role in the innate immune response by identifying patterns of pathogen-specific molecules.

Step-by-step explanation:

Pattern recognition receptors (PRRs) are membrane-bound receptors that recognize characteristic features of a pathogen and molecules released by stressed or damaged cells. They play a crucial role in the innate immune response by identifying patterns of pathogen-specific molecules using recognition receptors.

Option c) PRRs are able to bind to molecules widely expressed by microbes and host cells is the correct statement regarding PRRs. PRRs can bind to molecules expressed by both pathogens and host cells, enabling detection of both intracellular and extracellular pathogens.

Option a) PRRs can recognize host-associated molecules such as MHC class I molecules is incorrect. PRRs are primarily involved in recognizing pathogen-specific molecules.

Option b) PRRs are somatically generated by B and T cells is incorrect. PRRs are not generated by B and T cells, but are instead present on innate immune cells.

Option d) PRRs vary greatly between individuals is incorrect. PRRs are highly conserved and do not vary greatly between individuals.