Final answer:
The Indian Removal Act of 1830 led to the forced removal of the Cherokee Nation, among other tribes, to the western United States, in a journey infamously known as the Trail of Tears.
Step-by-step explanation:
The Indian Removal Act of 1830 resulted in significant consequences for Native American tribes. This federal act led to the forced relocation of Native tribes from their ancestral lands east of the Mississippi River to territories in the west. The Cherokee Nation was one such tribe that suffered greatly from this policy, enduring the infamous journey known as the Trail of Tears.
As a direct result of the Indian Removal Act, members of the Cherokee Nation were forced to move to the western United States, present-day Oklahoma, which took nine months and resulted in approximately 4,000 to 8,000 deaths due to severe conditions experienced along the way. The Choctaw, Creek, Seminole, and Chickasaw were also among the tribes forcibly removed.
The Act allowed President Andrew Jackson to negotiate removal treaties with Native tribes, leading to a brutal and tragic chapter in United States history that resulted in death, displacement, and long-term impact on Native American communities.